Research

Dr Pirjo Pärnänen (Associate Professor in Oral Microbiology, DMD, PhD) has been researching fermented lingonberry juice for over 15 years, and has conducted a number of clinical studies with impressive outcomes.

 

Results of studies are outstanding

Laboratory and clinical studies have shown a reduction in dental plaque and bleeding of the gums, and additionally antimicrobial, anti-inflammatory, anti-cancerous, and antioxidant properties. Caries-related Streptococcus mutans and candidosis- related Candida levels are reduced as well as periodontal disease- related pathogen levels. Levels of lactobacilli on the other hand are increased, which is thought to be a beneficial probiotic effect balancing the oral microbiota.

 

Research papers

Here are a few examples of publications by Dr Pirjo Pärnänen and her peers:

Topic Publication
Lingonberry (Vaccinium vitis-idaea L.) Fruit Phenolic Bioactivities—A Review of In Vitro and In Vivo Human Studies Microorganisms Journal,
September 2024
Oral Anti-Inflammatory and Symbiotic Effects of Fermented Lingonberry Juice—Potential Benefits in IBD Nutrients Journal,
August 2024
Long-term remission of candidiasis with fermented lingonberry mouth rinse in an adult patient with APECED International Journal of Infectious Diseases,
May 2024
Fermented lingonberry juice's effects on active MMP-8 (aMMP-8), bleeding on probing (BOP), and visible plaque index (VPI) in dental implants. A clinical pilot mouthwash study Clinical and Experimental Dental Research,
July 2022
Effects of Fermented Lingonberry Juice Mouthwash on Salivary Parameters-A One-Year Prospective Human Intervention Study Dentistry Journal,
April 2022
Lingonberry polyphenols: Potential SARS-CoV-2 inhibitors as nutraceutical tools? Physiological Report,
February 2021
Isolation, characterization and regulation of moonlighting proteases from Candida glabrata cell wall Microbial Pathogenesis,
October 2020
Antimicrobial and anti-inflammatory lingonberry mouthwash- a clinical pilot study in the oral cavity Microorganisms,
September 2019
Fermented lingonberry juice inhibits oral tongue squamous cell carcinoma invasion in vitro similarly to curcumin In Vivo,
September 2018
Effect of Fermented Lingonberry Juice on Candida glabrata Intracellular Protein Expression International Journal of Dentistry,
March 2017
A preparation for balancing the composition of the oral microbial flora EP 2585087B1, 2017